We are in tireless pursuit of breakthroughs that improve patients' lives. We create innovations daily to make the world a healthier place. It was Charles Pfizer's founding vision, and it still holds true today. Studies show what intuition tells us: that purpose-driven companies perform better, are more creative, draw and keep the best professionals, and know how to harness the power of those individuals. Pfizer's purpose—Breakthroughs that transform patients' lives—powers everything we do and shows our passion for building on our legacy as one of the most meaningful contributors of good to the world. Each word in our purpose has importance and embodies the value we strive to bring to patients and society. Our purpose makes certain that patients remain at the centre of all we do. We fulfill our purpose by sourcing the best science in the world, collaborating with others in the healthcare system to improve access to our medicines, employing digital technologies to enhance our drug discovery and development, as well as patient outcomes, and spearheading the conversation to advocate for pro-innovation/pro-patient policies. Every determination we make, and every action we take is done with the patient in mind—and to foster an environment where breakthroughs can thrive.